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Medicines are closely related to our lives. From cold medicine, painkillers, to prescription drugs, etc., they are closely related to our health. The selection of additives is particularly important in the development and production of drugs. They not only affect the physical an
Medicines are closely related to our lives. From cold medicine, painkillers, to prescription drugs, etc., they are closely related to our health.
The selection of additives is particularly important in the development and production of drugs. They not only affect the physical and chemical properties of drugs, but also have a certain impact on the stability of drugs.
Among them, there is an additive - carboxymethyl cellulose sodium (CMC), which forms a complementary relationship with drugs based on its properties.
The role of CMC in the pharmaceutical industry:
1.Adhesive bonding. CMC, due to its good viscosity, can serve as an adhesive, effectively promoting the bonding between drug particles, improving the hardness and toughness of tablets, and making them less prone to breakage during storage and transportation.
2.Collapse. CMC can be used as a disintegrant to help tablets quickly disintegrate after administration, release drug components, and improve the bioavailability of drugs.
3.Suspended. CMC can effectively suspend drug particles and serve as a suspension agent to prevent their settling and aggregation, ensuring uniform dispersion of drugs in liquids, thereby improving drug stability and bioavailability.
4.Film formation. CMC can be used as a coating material for tablets, forming a smooth and uniform thin film. This film can protect the drug from external environmental factors such as humidity, oxygen, and light damage, thereby extending the shelf life of the drug. At the same time, it can also control the release rate of drugs, allowing them to be released at a predetermined rate in the body, improving the efficacy and safety of drugs.
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